MultiVersus is a team-based platform fighting game where players battle each other on various stages with the goal of knocking their opponent off the stage by inflicting enough damage. While solo play and free-for-all options are available, the game places a strong emphasis on cooperative play, with most attacks designed to be used in tandem with a partner.

MultiVersus offers players the ability to customize their characters through the use of a perk system, which allows players to equip passive abilities that will also impact their team mate in a two-player team. These abilities, known as Signature Perks, are unique to each character and directly affect their attributes and skills. If players on the same team equip matching perks, the effects of these perks are amplified.